5-Isoxazolamine, 3-cyclopropyl- - Names and Identifiers
5-Isoxazolamine, 3-cyclopropyl- - Physico-chemical Properties
Molecular Formula | C6H8N2O
|
Molar Mass | 124.14 |
Density | 1.296±0.06 g/cm3(Predicted) |
Boling Point | 294.5±28.0 °C(Predicted) |
pKa | -0.59±0.50(Predicted) |
Sensitive | IRRITANT |
MDL | MFCD08558463 |
5-Isoxazolamine, 3-cyclopropyl- - Introduction
3-Cyclopropyl-1,2-oxazol-5-amine is an organic compound with the molecular formula C5H7N2O. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White to light yellow solid.
-Melting point: About 90-92 ° C.
-Boiling point: About 300 ° C.
-Solubility: Soluble in organic solvents, such as dichloromethane, ethanol, chloroform, etc.
Use:
- 3-Cyclopropyl-1,2-oxazol-5-amine is an important intermediate, which can be used in a variety of reactions in organic synthesis, such as cyclization, Amination of carbonyl compounds and so on.
-It is often used to prepare biologically active compounds, such as potential drug molecules.
Method:
- 3-Cyclopropyl-1,2-oxazol-5-amine can be synthesized by the following steps:
(1) Benzyl acetone was prepared by the reaction of benzaldehyde and acetone.
(2) Cyclopropyl alcohol was prepared by reacting benzyl acetone with propyl alcohol.
(3) Cyclopropyl alcohol is reacted with a dehydrating agent to produce 3-cyclopropylisoxazole.
(4) Finally, 3-Cyclopropyl-1,2-oxazol-5-amine was prepared by reacting 3-Cyclopropyl-1 with ammonia.
Safety Information:
-Specific hazard and toxicity data for 3-Cyclopropyl-1,2-oxazol-5-amine may vary depending on the route of human exposure. Therefore, when using or coming into contact with this compound, the relevant safety practices should be followed.
-This compound may be irritating and direct contact with skin, eyes and mucous membranes should be avoided.
-During storage and handling, appropriate ventilation and personal protective measures should be taken, including gloves, safety glasses and protective masks.
-Please consult relevant safety information and chemical suppliers for more accurate safety information.
Last Update:2024-04-09 21:00:56